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Latest News

14th September, 2018

Peter Fisher

ECCH offers its warm condolences to Peter Fisher’s family after his tragic death in a bike accident in London on 15th August 2018. The homeopathy community globally mourns for the ...

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17th November, 2017

Keep Antibiotics Working, European Antibiotic Awareness Day

European Antibiotic Awareness Day is on the 18th November 2017. The WHO, UN and other organizations are calling for awareness about the threat to public health of antibiotic resistance and ...

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Future Events

New study finds ultra-diluted remedies have cytotoxic effects on breast cancer cells

Abstract

The use of ultra-diluted natural products in the management of disease and treatment of cancer has generated a lot of interest and controversy. We conducted an in vitro study to determine if products prescribed by a clinic in India have any effect on breast cancer cell lines. We studied four ultra-diluted remedies (Carcinosin, Phytolacca, Conium and Thuja) against two human breast adenocarcinoma cell lines (MCF-7 and MDA-MB-231) and a cell line derived from immortalized normal human mammary epithelial cells (HMLE). The remedies exerted preferential cytotoxic effects against the two breast cancer cell lines, causing cell cycle delay/arrest and apoptosis.

These effects were accompanied by altered expression of the cell cycle regulatory proteins, including down-regulation of phosphorylated Rb and upregulation of the CDK inhibitor p27, which were likely responsible for the cell cycle delay/arrest as well as induction of the apoptotic cascade that manifested in the activation of caspase 7 and cleavage of PARP in the treated cells. The findings demonstrate biological activity of these natural products when presented at ultra-diluted doses. Further indepth studies with additional cell lines and animal models are warranted to explore the clinical applicability of these agents.

A full version of the study can be downloaded here:
http://www.spandidos-publications.com/ijo/article.jsp?article_id=ijo_36_2_395

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